[Somatocrinin (GRF) stimulates the liberation of biologically active somatotropin (GH) in adult man].

G Sassolas, J P Boissel, R Cohen, P Chatelain, S Laporte, J Galleyrand, H Cohen, S Ferry, P Maire
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Abstract

Intravenous injection of four doses (75, 150, 300, 600 micrograms) of synthetic somatocrinin (GRF 44) greatly increases serum growth hormone concentrations in ten adult normal men in contrast to placebo. Mean peak values were identical. Plasma GH released under GRF stimulation was able to stimulate proliferation of NB2 cells.

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[生长激素(GRF)刺激成年男性生物活性生长激素(GH)的释放]。
与安慰剂相比,静脉注射四种剂量(75、150、300、600微克)的合成生长激素(GRF 44)大大增加了10名成年正常男性的血清生长激素浓度。平均峰值相同。GRF刺激下释放的血浆GH能够刺激NB2细胞的增殖。
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