{"title":"Experimental auto-allergic sialoadenitis in male rats.","authors":"D H Dean, R N Hiramoto","doi":"10.1111/j.1600-0714.1984.tb01401.x","DOIUrl":null,"url":null,"abstract":"<p><p>Induced auto-allergic lesions in the submandibular glands of rats were studied by immunofluorescence. Direct staining with a goat anti-rat IgG conjugate was negative. Indirect immunofluorescence revealed a high incidence of anti-salivary-duct antibodies in sera from both control and experimental groups. In individual rats, no relationship was found between the presence or absence of serum anti-salivary antibodies and the presence or absence of salivary auto-allergic lesions. We conclude that the antibodies demonstrated do not play a role in the pathogenesis of the disease.</p>","PeriodicalId":16672,"journal":{"name":"Journal of oral pathology","volume":"13 1","pages":"63-8"},"PeriodicalIF":0.0000,"publicationDate":"1984-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0714.1984.tb01401.x","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1600-0714.1984.tb01401.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Induced auto-allergic lesions in the submandibular glands of rats were studied by immunofluorescence. Direct staining with a goat anti-rat IgG conjugate was negative. Indirect immunofluorescence revealed a high incidence of anti-salivary-duct antibodies in sera from both control and experimental groups. In individual rats, no relationship was found between the presence or absence of serum anti-salivary antibodies and the presence or absence of salivary auto-allergic lesions. We conclude that the antibodies demonstrated do not play a role in the pathogenesis of the disease.
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