{"title":"Amplification and over-expression of the c-myc gene in Morris hepatomas.","authors":"K Hayashi, R Makino, T Sugimura","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Morris hepatoma 7794A was found to have its c-myc gene amplified 5- to 10-fold. The over-expression of c-myc was observed in all three hepatomas studied (Morris hepatomas 5123D, 7136A and 7794A), although in the first two instances the c-myc genes were not amplified. Over-expression or deregulation of c-myc seems to be a general phenomenon associated with hepatoma.</p>","PeriodicalId":12660,"journal":{"name":"Gan","volume":"75 6","pages":"475-8"},"PeriodicalIF":0.0000,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gan","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Morris hepatoma 7794A was found to have its c-myc gene amplified 5- to 10-fold. The over-expression of c-myc was observed in all three hepatomas studied (Morris hepatomas 5123D, 7136A and 7794A), although in the first two instances the c-myc genes were not amplified. Over-expression or deregulation of c-myc seems to be a general phenomenon associated with hepatoma.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
