Amygdaloid kindling in Papio cynocephalus and subsequent recurrent spontaneous seizures.

M E Corcoran, D P Cain, J A Wada
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引用次数: 7

Abstract

Three baboons, Papio cynocephalus, (two photosensitive and one nonphotosensitive) were subjected to amygdaloid kindling. Electroclinical profile of seizure development-developed seizure compares very favourably to that described in photosensitive baboons, Papio papio, with rapid seizure progression and ultimate emergence of Stage 5 bisymmetrical and bisynchronous generalized convulsive state. In addition, one baboon developed spontaneous recurrent seizures which were identical to the kindled Stage 5 seizure. It is concluded that the state of exceptional seizure susceptibility observed in Papio papio is shared by Papio cynocephalus, although photosensitivity and kindled generalized convulsion appear to be independent variables.

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脑瘫患者的杏仁核体点燃和随后的复发性自发性癫痫发作。
对三只狒狒(两只光敏一只不光敏)进行杏仁核点燃。癫痫发作发展的电临床特征与光敏性狒狒(Papio Papio)的癫痫发作相比非常有利,癫痫发作进展迅速,最终出现第5期双对称和双同步全面性惊厥状态。此外,一只狒狒出现了自发的复发性癫痫发作,这与点燃的第五阶段癫痫发作相同。结论:尽管光敏性和引燃性全身性惊厥是独立的变量,但在木瓜中观察到的异常癫痫易感性状态与cynocephalus相同。
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