[Lung injury after use of respiratory revival materials sterilized with ethylene oxide].

A Castot, G Riboulet-Delmas, M L Efthymiou, D Robardey, F Manela, O Muzard, A Goldstein
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Abstract

One of the most used method of medical appliances sterilization uses ethylene oxide. At high concentration, this very reactive product, causes caustic burns of skin and mucous membranes. In one case of acute pulmonary oedema, levels of ethylene oxide in the endotracheal catheter were discovered. This led us to review the toxicological data on this substance. It should be emphasized that the sterilization and the desorption according to simple and precise rules should prevent such acute accidents.

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[使用环氧乙烷灭菌呼吸再生材料后肺损伤]。
环氧乙烷是常用的医疗器械灭菌方法之一。高浓度时,这种反应性很强的产物会引起皮肤和粘膜的腐蚀性烧伤。在一例急性肺水肿中,发现气管内导管中有环氧乙烷的水平。这促使我们审查了该物质的毒理学数据。需要强调的是,按照简单而精确的规则进行灭菌和解吸,可防止此类急性事故的发生。
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