Alcoholism and depression.

Substance and alcohol actions/misuse Pub Date : 1983-01-01
G Winokur
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Abstract

There are a variety of ways in which depression and alcoholism are related. These include the possibility of a person suffering from two relatively frequent diseases by chance alone. Secondly, on withdrawal from alcoholism depressive symptoms occur; these are rather short lived. Third, a secondary depression is seen in a large number of chronic alcoholics. Secondary depression is an ordinary depressive illness which manifests itself in the course of another primary illness, in this case alcoholism. There is no evidence that secondary mania exists to alcoholism. Finally, another type of relationship is familial. In a large number of alcoholics, such people come from families where depression also exists. This depression is called a depression spectrum disease. Depression spectrum disease is a depressive illness which occurs in an individual who comes from a family where alcoholism exists. Such a family may also contain other depressives but no manics. Depression spectrum disease patients are likely to have a relatively early onset, and are likely to show many problems in living and unstable personality characteristics. They are likely to be normal suppressors on the dexamethasone suppression test.

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酗酒和抑郁。
抑郁症和酒精中毒之间有多种联系。其中包括一个人仅仅偶然患上两种相对常见的疾病的可能性。第二,戒酒后出现抑郁症状;这些都是相当短暂的。第三,继发性抑郁症见于大量慢性酗酒者。继发性抑郁症是一种普通的抑郁症,在另一种原发疾病的过程中表现出来,在这种情况下是酒精中毒。没有证据表明酒精中毒后存在继发性躁狂。最后,另一种关系是家庭关系。在大量酗酒者中,这些人来自同样存在抑郁症的家庭。这种抑郁症被称为抑郁症谱系疾病。抑郁谱系疾病是一种抑郁症,发生在酗酒家庭的个体身上。这样的家庭也可能有其他抑郁症患者,但没有狂躁症患者。抑郁症谱系疾病患者可能发病相对较早,并且可能表现出许多生活问题和不稳定的人格特征。在地塞米松抑制试验中,它们可能是正常的抑制因子。
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