[Serotype and antibiotic resistance of pneumococci isolated at the Aix-en-Provence Hospital Center].

Le Poumon et le coeur Pub Date : 1983-01-01
H Chardon, F Zarrouk, P Geslin, E Jardel, R Poirier
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Abstract

Over a 2 year period from April 1980 to April 1982, 240 pneumococci isolated from amongst 208 patients during 216 infectious episodes were serotyped. Sensitivity to standard antibiotics was determined for 209 of these strains. Pneumococci are divided into 33 serotypes. The vaccination cover provided by the vaccine currently commercially available is 70%. AUSTRIAN and GESLIN feel that the surveillance of bacteraemias is the most effective method for the choice of vaccine formula in order to eliminate the bias due to healthy carriers. In the present study, pneumococci isolated from 41 bacteraemias came from 14 serotypes and vaccine cover was 90%. Amongst 209 strains of Streptococcus pneumoniae, 25.8% were resistant to tetracyclines, 10.5% to sulphonamides, 6.6% to chloramphenicol, 5.7% to erythromycin, 2.8% to co-trimoxazole and none to penicillin.

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[普罗旺斯艾克斯医院中心分离的肺炎球菌的血清型和抗生素耐药性]。
在1980年4月至1982年4月的2年间,从216次感染发作的208例患者中分离出240株肺炎球菌进行血清分型。其中209株对标准抗生素敏感。肺炎球菌分为33种血清型。目前市售疫苗提供的疫苗接种率为70%。奥地利和GESLIN认为,菌血症监测是选择疫苗配方的最有效方法,以消除因健康携带者而产生的偏差。在本研究中,从14种血清型的41种菌血症中分离出肺炎球菌,疫苗覆盖率为90%。209株肺炎链球菌对四环素耐药25.8%,对磺胺类耐药10.5%,对氯霉素耐药6.6%,对红霉素耐药5.7%,对复方新诺明耐药2.8%,对青霉素无耐药。
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[Drug-induced respiratory disorders]. [Effector functions of the polynuclear eosinophil]. [Small cell epithelioma in the Rhône-Alp region: changes in incidence between 1970 and 1980]. [Granular cell bronchial tumors. General features, developmental and therapeutic aspects. Apropos of 4 new cases]. [A rare tumor: benign sclerosing pneumocytoma with an intrascissural development].
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