Hormonal response to LH-RH application in normal women.

Endokrinologie Pub Date : 1982-07-01
M Cvetković, H Behrman, N Papić, V Sulović, O Genbacev
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Abstract

The postovulatory effects of pharmacological doses of LH-RH on progesterone and LH plasma concentrations have been demonstrated. LH-RH injected on the 16th and 18th day of the menstrual cycle induces the discharge of LH; the second application results in a weaker discharge, indicating that the pituitary stores are exhausted. A LH-RH injection induces a decrease of the plasma progesterone concentration which becomes evident after a delay of 26 hours. A statistically significant correlation between LH and progesterone plasma concentrations was obtained 26 h after the administration of LH-RH.

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正常女性应用rh - rh时的激素反应。
药理学剂量的LH- rh对黄体酮和LH血浆浓度的排卵后影响已被证实。月经周期第16、18天注射LH- rh可诱导LH排出;第二次应用导致较弱的放电,表明垂体储存已耗尽。rh - rh注射诱导血浆黄体酮浓度降低,延迟26小时后变得明显。给药26 h后,LH与黄体酮血浆浓度有统计学意义的相关。
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