Bone marrow transplantation: current status.

Pathobiology annual Pub Date : 1982-01-01
R Dinsmore, R J O'Reilly
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Abstract

During the past decade, the results of BMT have dramatically improved with an increasing number of long-term survivors in diseases that were previously fatal. These results are gratifying and probably indicate an increased cure rate through the use of marrow transplantation. However, the recent advances have occurred partially due to better patient selection for transplantation as in the untransfused aplastic patient or the leukemic patient in early remission. Problems remain which still limit both the success and applicability of marrow transplantation. These are the challenges of the 1980s which, if overcome, will lead to the extension of BMT to other blood and genetic diseases.

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骨髓移植:现状。
在过去的十年中,随着以前致命疾病的长期幸存者人数的增加,BMT的结果有了显著改善。这些结果是令人满意的,可能表明通过使用骨髓移植增加治愈率。然而,最近的进展部分是由于在未输血的再生障碍性白血病患者或早期缓解的白血病患者中更好地选择了移植患者。仍然存在一些问题,这些问题限制了骨髓移植的成功和适用性。这些是1980年代的挑战,如果克服这些挑战,将导致BMT扩展到其他血液和遗传疾病。
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