Role of a secretagogue immunoglobulin in gastric acid secretion.

S Dobi, B Lenkey
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Abstract

Results of this study showed that in a considerable number of patients with duodenal ulcer a globulin of the IgG class was responsible for the enhancement of HCl secretion. This secretagogue globulin appeared to combine directly with the H2 receptors of the parietal cells thereby increasing hydrochloric acid output without the formation of antigen-antibody complex.

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促分泌免疫球蛋白在胃酸分泌中的作用。
本研究结果表明,在相当数量的十二指肠溃疡患者中,一种IgG类的球蛋白负责增强HCl的分泌。这种促分泌球蛋白似乎直接与壁细胞的H2受体结合,从而增加盐酸的输出,而不形成抗原-抗体复合物。
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