[Localization of pyruvate kinase M1 (ATP pyruvate phosphotransferase-2.7.1.40) in nervous tissue of the rat. Preliminary results].

P Gali, J M Boutry, J J Hauw, L Hartmann
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Abstract

The M1 pyruvate kinase has been localized in macroneuron's cytoplasm of nervous tissue of adult Rat, in situ as well as in tissue culture. Three methods have been used: histoenzymology, immunoenzymology and immunofluorescence, combined with Nomarski optics. This enzymatic localization may suggest a metabolic or differenciated fonctionnal state of the nerve cell.

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丙酮酸激酶M1 (ATP丙酮酸磷酸转移酶2.7.1.40)在大鼠神经组织中的定位。初步结果)。
M1丙酮酸激酶在成年大鼠神经组织的大神经元细胞质、原位和组织培养中均有定位。采用组织酶学、免疫酶学和免疫荧光三种方法,结合诺玛斯基光学。这种酶定位可能提示神经细胞的代谢或分化功能状态。
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