[Anti-elastase of human pancreas: preparation and biological interest].

M Rabaud, J Tribouley-Duret, F Lefebvre, C Desgranges, H Bricaud
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Abstract

The present paper deals with the use of a new technique in type II human pancreatic elastase studies based on the use of a reversible immune-adsorbent which provides a unique specificity. According to the type of ligand linked on activated Sepharose, the elastase or its antibody in Rabbit could be obtained, in very pure form, in a one step process. The anti-human pancreatic elastase II, which specifically inhibits the enzyme, may be used in therapy whenever the elastase-inhibitor system becomes unbalanced.

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人胰腺抗弹性酶的制备及其生物学意义。
本文介绍了一种基于可逆免疫吸附剂的II型人胰腺弹性酶研究的新技术,该技术具有独特的特异性。根据连接在活化的Sepharose上的配体的类型,兔体内的弹性酶或其抗体可以一步获得,纯度很高。抗人胰腺弹性酶II,其特异性抑制酶,可用于治疗弹性酶抑制剂系统变得不平衡。
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