M Rabaud, J Tribouley-Duret, F Lefebvre, C Desgranges, H Bricaud
{"title":"[Anti-elastase of human pancreas: preparation and biological interest].","authors":"M Rabaud, J Tribouley-Duret, F Lefebvre, C Desgranges, H Bricaud","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The present paper deals with the use of a new technique in type II human pancreatic elastase studies based on the use of a reversible immune-adsorbent which provides a unique specificity. According to the type of ligand linked on activated Sepharose, the elastase or its antibody in Rabbit could be obtained, in very pure form, in a one step process. The anti-human pancreatic elastase II, which specifically inhibits the enzyme, may be used in therapy whenever the elastase-inhibitor system becomes unbalanced.</p>","PeriodicalId":10605,"journal":{"name":"Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles","volume":"291 10","pages":"825-8"},"PeriodicalIF":0.0000,"publicationDate":"1980-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The present paper deals with the use of a new technique in type II human pancreatic elastase studies based on the use of a reversible immune-adsorbent which provides a unique specificity. According to the type of ligand linked on activated Sepharose, the elastase or its antibody in Rabbit could be obtained, in very pure form, in a one step process. The anti-human pancreatic elastase II, which specifically inhibits the enzyme, may be used in therapy whenever the elastase-inhibitor system becomes unbalanced.