Intraocular lenses: experience at The Wilmer Institute.

Australian journal of ophthalmology Pub Date : 1983-05-01
W J Stark, A E Maumenee, W R Fagadau, L W Hirst, M B Datiles
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Abstract

Nine hundred and thirty-eight consecutive primary intraocular lens (IOL) implant cases performed at The Wilmer Institute during the past six years by two surgeons were reviewed. Progressive corneal endothelial cell loss and an increased rate of late-onset corneal oedema were detected in the group with the Morcher (European) four-loop iris-clip Binkhorst IOLs. A higher rate of clinically-significant cystoid macular oedema developed in eyes with the American-manufactured four-loop Binkhorst lens, presumably from chronic iritis caused by contaminants on the IOLs. Our short-term results with the American-manufactured Shearing-type IOLs implanted at the time of extracapsular cataract extraction are encouraging, with 96% of cases achieving 20/40 vision or better, excluding those with known macular degeneration or amblyopia. Analysis of data submitted to the United States Food and Drug Administration (FDA) indicates that most of the four classes of intraocular lenses (anterior chamber, pupillary-supported, iridocapsular, and posterior chamber) are safe and effective at one-year follow-up. During the past three years there has been a gradual shift of preference in the type of IOLs being implanted--away from pupillary-supported and iridocapsular IOLs and, in part, from anterior chamber IOLs, to posterior chamber IOLs. A continued conservative approach to IOL implantation is recommended.

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人工晶状体:在威尔默研究所的经历。
在过去的六年里,两位外科医生在Wilmer研究所连续进行了938例原发性人工晶状体(IOL)植入手术。在Morcher(欧洲)四环虹膜夹Binkhorst iol组中检测到进行性角膜内皮细胞丢失和晚发性角膜水肿率增加。使用美国制造的四环Binkhorst晶状体时,可能是由于人工晶状体上的污染物引起的慢性虹膜炎,导致临床上明显的囊样黄斑水肿的发生率较高。我们在白内障囊外摘出术中植入美国制造的剪切型人工晶状体的短期结果令人鼓舞,96%的患者视力达到20/40或更好,排除了已知的黄斑变性或弱视患者。提交给美国食品和药物管理局(FDA)的数据分析表明,在一年的随访中,四类人工晶状体(前房、瞳孔支撑、虹膜囊和后房)中的大多数都是安全有效的。在过去的三年中,人们对人工晶体植入类型的偏好逐渐发生了变化——从瞳孔支撑型和虹膜囊型人工晶体,部分从前房型人工晶体转向后房型人工晶体。建议继续采用保守方法植入人工晶状体。
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