[Thermal isolation of the heart by means of a plastic foam pad during surgical cooling of the heart: experimental study].

Le Poumon et le coeur Pub Date : 1982-01-01
J A Barra, D Deredec, L Tanguy, A Pavie, P Legendre, D de La Faye, Y Raut, C Cabrol
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Abstract

Maintenance of myocardial cooling during aortic clamping is a problem encountered currently during heart surgery. A plastic foam isolation pad was studied. Eight animals (pigs weighing 50 kg) were placed on extracorporeal circulation, 4 of them constituting the control group (A). Two coronary injections of a cardioplegic solutions were administered, the first at the time of aortic clamping and the second 30 minutes later. The myocardium of the 4 animals in the treated group (B) was isolated with the foam pad, and this significantly prolonged the "cold" effect of the cardioplegic. Ten minutes after injection of the cardioplegic, temperature of the total myocardial mass with isolation was between 10.7 and 12 degrees C, as against 16 to 18 degrees C in the reference group (p less than 0.05). By the 20th minute, the isolated myocardium was at approximately 15 degrees C as against 22 degrees C in group A (p less than 0.01). Finally, by the 30th minute, temperature in group B was 17 degrees C as against 23 degrees C in group A (p less than 0.01). Reheating of the heart was significantly slowed by thermal isolation, though the limit of 15 degrees C was reached by the 20th minute. To ensure that myocardial temperature remains below this limit when the foam pad is employed, further injections of cardioplegic solutions are necessary every 20 minutes.

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[在心脏手术冷却过程中用泡沫塑料垫对心脏进行热隔离:实验研究]。
主动脉夹持期间维持心肌冷却是目前心脏手术中遇到的一个问题。对泡沫塑料隔离垫进行了研究。8只动物(体重50 kg)进行体外循环,其中4只作为对照组(A)。两次冠状动脉注射一种心脏麻痹溶液,第一次在主动脉夹紧时注射,第二次在30分钟后注射。治疗组(B) 4只动物用泡沫垫隔离心肌,明显延长了心脏麻痹的“冷”作用。心脏麻痹注射后10分钟,隔离心肌团块总温度为10.7 ~ 12℃,对照组为16 ~ 18℃(p < 0.05)。到20分钟,离体心肌温度约为15℃,而A组为22℃(p < 0.01)。最后,在30分钟时,B组的体温为17℃,而A组为23℃(p < 0.01)。通过热隔离,心脏的再加热明显减慢,尽管在20分钟时达到了15摄氏度的极限。在使用泡沫垫时,为了确保心肌温度保持在这个限度以下,每20分钟需要进一步注射心脏麻痹溶液。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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