[Angioimmunoblastic lymphadenopathy with cutaneous leukocytoclastic vasculitis. 2 cases].

La Nouvelle presse medicale Pub Date : 1982-12-11
P Arlet, M Laroche, G Delsol, G Seigneuric, M Duffaut, Y Le Tallec
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Abstract

In two patients with similar symptoms (fever, very poor general condition, skin rash, pulmonary involvement, multiple lymphadenopathy and phlebitis) pathological examination disclosed angioimmunoblastic lesions in lymph nodes and leucocytoblastic vascularities in the skin. While all cases published so far were exceptional, the clinical and pathophysiological findings were strikingly similar in these two cases, and the possibility of a special nosological entity is considered. If relapses are to be avoided, both patients will require continuous high dosage corticosteroid therapy, which aggravates the long-term prognosis.

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血管免疫母细胞性淋巴结病伴皮肤白细胞破坏性血管炎。2例)。
2例患者症状相似(发热、全身状况极差、皮疹、肺部受累、多发性淋巴结病和静脉炎),病理检查发现淋巴结血管免疫病变和皮肤白细胞增生血管。虽然到目前为止发表的所有病例都是例外,但这两个病例的临床和病理生理结果惊人地相似,并且考虑了特殊疾病实体的可能性。如果要避免复发,两名患者都需要持续的高剂量皮质类固醇治疗,这会加重长期预后。
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