{"title":"Malignant change of laryngeal papillomas: a case report.","authors":"R J Keim","doi":"10.1177/019459988008800626","DOIUrl":null,"url":null,"abstract":"<p><p>A major controversy surrounding juvenile papilloma is whether or not these lesions ever spontaneously undergo malignant change. One view contends that malignant change never takes place unless the lesion is irradiated. Presented is a 22-year-old man who suddenly develops features of extensive malignant invasion of his neck and mediastinum but has no history of irradiation.</p>","PeriodicalId":76298,"journal":{"name":"Otolaryngology and head and neck surgery","volume":"88 6","pages":"773-7"},"PeriodicalIF":0.0000,"publicationDate":"1980-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/019459988008800626","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Otolaryngology and head and neck surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/019459988008800626","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
A major controversy surrounding juvenile papilloma is whether or not these lesions ever spontaneously undergo malignant change. One view contends that malignant change never takes place unless the lesion is irradiated. Presented is a 22-year-old man who suddenly develops features of extensive malignant invasion of his neck and mediastinum but has no history of irradiation.
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