[Microglandular hyperplasia of the cervix: reevaluation of the polyp (author's transl)].

T Jobo, H Kuramoto, T Morisawa
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Abstract

Microglandular hyperplasia which may not be familiar in this country is a polypoid lesion of the cervix and has been noticed as the lesion sustained by contraceptive pills. The retrospective study was performed to clarify whether or not this lesion have been enclosed into diagnosis of cervical polyp at routine clinic. 1. Among 895 cases of cervical polyp resected at our clinic during 7 years from 1971, 7 microglandular hyperplasias were found, showing 0.8% of the incidence. 2. Ages of the 7 patients ranged from 42 to 52 years, and the average was 45.7. Three cases complained of metrorrhagia. 3. One woman was taking oral contraceptives and the other was on hormonal therapy. No patient was pregnant. 4. Polyps with microglandular hyperplasia were usually above the size of small finger tip. In one case, a large papillary mass (3.0 x 3.5 cm) resembling to carcinoma of the cervix was experienced. 5. There were no characteristic findings in cytology except a case with enlarged and vesicular cells. 6. Histologically, the lesion consists of numerous microglandular spaces lined by regular cuboidal or flat cells without atypism. The eosinophilic cytoplasms are not vacuolated. Glands are not clearly demarcated from edematous stroma. This change may be mistaken for adenocarcinoma.

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[宫颈微腺增生:对息肉的重新评估[作者简介]。
微腺体增生是宫颈息肉样病变,在我国可能并不常见,由于服用避孕药引起的病变已引起注意。回顾性研究的目的是为了澄清这种病变是否被纳入宫颈息肉的常规临床诊断。1. 自1971年以来7年间,本院共切除895例宫颈息肉,发现微腺增生7例,占发生率0.8%。2. 7例患者年龄42 ~ 52岁,平均45.7岁。3例主诉子宫出血。3.一名妇女服用口服避孕药,另一名接受激素治疗。没有病人怀孕。4. 息肉伴微腺增生,大小一般大于小指尖。在一个病例中,有一个大的乳头状肿块(3.0 x 3.5 cm),类似于子宫颈癌。5. 在细胞学上没有特征性的发现,除了一例增大和泡状细胞。6. 组织学上,病变由许多由规则的立方体或扁平细胞排列的微腺腔组成,无异型性。嗜酸性细胞质不空泡化。腺体与水肿间质界限不清。这种变化可能被误认为是腺癌。
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