Predicting stimulant effectiveness in hyperactive children with a repeatable neuropsychological battery: A preliminary study

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI:10.1016/0364-7722(81)90006-0

Barry E. Golinko, Phillip M. Rennick, Ronald F. Lewis

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引用次数: 4

Abstract

1.
1. A double blind assessment of change on neuropsychological tests was used to determine whether psychostimulant medication would improve a particular hyperactive child's performance on tasks requiring attention and learning.
2.
2. Thirteen hyperactive children were tested on a repeatable battery of cognitive-perceptual-motor tasks under each of three conditions: low dose of dextroamphetamine sulfate; high dose; placebo.
3.
3. A ranking system was used to determine the comparative efficacy of doses in terms of overall performance on the battery. Results showed that d-amphetamine was more effective than placebo for 11 of the 13 children.
4.
4. The advantages of the assessment method for the physician, in terms of titrating doses quickly and in continuing to monitor dose effectiveness in long-term follow-up, were discussed.

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用可重复的神经心理学电池预测多动症儿童的兴奋剂有效性:一项初步研究

1.1. 采用双盲法评估神经心理测试的变化，以确定精神兴奋剂药物是否会改善一个特定的多动症儿童在需要注意力和学习的任务上的表现。13名多动症儿童在三种条件下接受了一组可重复的认知-知觉-运动任务测试:低剂量的硫酸右苯丙胺;高剂量;placebo.3.3。根据电池的整体性能，使用了一个排名系统来确定剂量的比较功效。结果显示，在13名儿童中，有11名儿童服用d-安非他明比安慰剂更有效。讨论了评估方法在快速滴定剂量和在长期随访中继续监测剂量有效性方面对医生的优点。

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