[An experimental animal model of aortic coarctation].

Abstract

There was developed a model of animal experiments for clearing up some questions in connection with the Coarctation aortae (for instance hypertension in the postoperative phase, hypertrophy in the left chamber of the heart and protection of myocardium during the operation). Stripes and ligatures of the aorta create a substrate deviating from the human disease. We put up a model of animal experiments in which the stenosis is produced by means of the extravascular application of electrical direct current of anodic polarization. The employment of direct current guarantees an extensive standardization and reproduction of experimental methodology.