Formalin stress reaction of germfree and conventional mice treated with Bordetella pertussis vaccine.

P Anderlik, M Wessely, I Szeri, Z Bános, I U Rápolthy, J Budai
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Abstract

Germfree and conventional mice responded similarly to pertussis vaccine treatment. In both groups, lymphocytosis and splenomegaly developed in a similar proportion. The formalin stress reaction of germfree and conventional mice with hypertrophic lymphoid organs induced by pertussis vaccine differed from that of untreated mice: the treated germfree and conventional mice showed a acute increase of lymphocytosis without an significant change in splenomegaly.

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百日咳博德泰拉疫苗对无菌小鼠和普通小鼠福尔马林应激反应的影响。
无菌小鼠和常规小鼠对百日咳疫苗治疗的反应相似。在两组中,淋巴细胞增多和脾肿大的发生比例相似。百日咳疫苗诱导淋巴样器官肥大的无菌和常规小鼠福尔马林应激反应与未处理小鼠不同:处理后的无菌和常规小鼠淋巴细胞增生急性增加,脾肿大无明显变化。
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