{"title":"Sub-optimal vigilance in patients with complete heart block: Influence of cardiac pacing and a “nootropic” substance","authors":"Krister R. Lagergren","doi":"10.1016/0364-7722(81)90092-8","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Mental performance of patients with artificial pacemakers was found to be impaired when the heart rate was lowered from 70 to 45 beats per minute in sitting position.</p></span></li><li><span>2.</span><span><p>2. The same lowering of the heart rate caused less impairment in supine body position.</p></span></li><li><span>3.</span><span><p>3. These findings are discussed with regard to cerebral blood flow; the impairment of performance at the lower heart rate being interpreted as caused by cerebral hypoxia.</p></span></li><li><span>4.</span><span><p>4. Under the same conditions Piracetam seems to have an effect which not only counteracts hypoxia, but also brings about enhancement of performance in some other way.</p></span></li><li><span>5.</span><span><p>5. The above mentioned findings seem to manifest themselves in EEG's evaluated by means of Spectral Parameter Analysis.</p></span></li></ul></div>","PeriodicalId":20801,"journal":{"name":"Progress in neuro-psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0364-7722(81)90092-8","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in neuro-psychopharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0364772281900928","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
1.
1. Mental performance of patients with artificial pacemakers was found to be impaired when the heart rate was lowered from 70 to 45 beats per minute in sitting position.
2.
2. The same lowering of the heart rate caused less impairment in supine body position.
3.
3. These findings are discussed with regard to cerebral blood flow; the impairment of performance at the lower heart rate being interpreted as caused by cerebral hypoxia.
4.
4. Under the same conditions Piracetam seems to have an effect which not only counteracts hypoxia, but also brings about enhancement of performance in some other way.
5.
5. The above mentioned findings seem to manifest themselves in EEG's evaluated by means of Spectral Parameter Analysis.
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