[Clinico-pathological data in infants with different types of nephrotic syndrome (author's transl)].

Abstract

Case reports including light- and electron microscopy about 4 children with infantile nephrotic syndrome are given. Histologic lesions were microcystic renal disease ("Finnish type"), diffuse glomerular mesangial sclerosis, glomerular mesangial proliferation and minimal changes in the 4 patients, respectively. Knowledge of the individual histologic lesion is essential for adequate therapy and the prognosis in all infants with nephrotic syndrome, except in cases with data proving the Finnish type; in some cases, the identification of individual histologic type will lead to adequate genetic counselling of the family.