M J Davicco, Y Faulconnier, V Coxam, H Dubroeucq, W Martin-Rosset, J P Barlet
{"title":"Systemic bone growth factors in light breed mares and their foals.","authors":"M J Davicco, Y Faulconnier, V Coxam, H Dubroeucq, W Martin-Rosset, J P Barlet","doi":"10.3109/13813459408996117","DOIUrl":null,"url":null,"abstract":"<p><p>There is a high incidence of bony pathology in race horses. Thus, plasma GH, IGF-1, osteocalcin (OC), calcium (Ca) and inorganic phosphorus (P) concentrations were measured in 12 healthy Selle Français foals and their dams during the first five months after birth. Plasma IGF-1 and OC concentrations were higher in foals than in mares (336 +/- 25 vs 230 +/- 18 ng/ml, P < 0.05; 52.5 +/- 3.2 vs 4.9 +/- 0.1 ng/mg, P < 0.01, respectively). A significant positive linear relationship could be established between these two parameters in foals (IGF-1 = 19 + 0.619 OC; P < 0.05). Another striking evidence was the increase in plasma IGF-1, OC and P concentrations observed during the first week of postnatal life. IGF-1, OC, P and Ca concentrations remained elevated during the experimental period, indicating an intense skeletal growth (confirmed by growth curve) in these animals.</p>","PeriodicalId":77008,"journal":{"name":"Archives internationales de physiologie, de biochimie et de biophysique","volume":"102 2","pages":"115-9"},"PeriodicalIF":0.0000,"publicationDate":"1994-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459408996117","citationCount":"22","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives internationales de physiologie, de biochimie et de biophysique","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/13813459408996117","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 22
Abstract
There is a high incidence of bony pathology in race horses. Thus, plasma GH, IGF-1, osteocalcin (OC), calcium (Ca) and inorganic phosphorus (P) concentrations were measured in 12 healthy Selle Français foals and their dams during the first five months after birth. Plasma IGF-1 and OC concentrations were higher in foals than in mares (336 +/- 25 vs 230 +/- 18 ng/ml, P < 0.05; 52.5 +/- 3.2 vs 4.9 +/- 0.1 ng/mg, P < 0.01, respectively). A significant positive linear relationship could be established between these two parameters in foals (IGF-1 = 19 + 0.619 OC; P < 0.05). Another striking evidence was the increase in plasma IGF-1, OC and P concentrations observed during the first week of postnatal life. IGF-1, OC, P and Ca concentrations remained elevated during the experimental period, indicating an intense skeletal growth (confirmed by growth curve) in these animals.
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