A Proposal That Would Ban Manufacture, Supply, and Use of All Fluoropolymers and Most Fluorinated Reagents within the Entire EU

IF 3.1 3区化学 Q2 CHEMISTRY, APPLIED Organic Process Research & Development Pub Date : 2023-08-02 DOI:10.1021/acs.oprd.3c00199

Nicholas D. Tyrrell*,

引用次数: 6

Abstract

A change to EU law is proposed that would lead to a ban on manufacture, supply, and use of most per- and polyfluorinated alkyl substance (PFAS) materials. The proposed EU definition of PFAS is extremely broad, including most fluoroalkyl materials, regardless of molecular weight. Thus, reagents as simple as trifluoroacetic acid through fluorinated intermediates to polymers such as PTFE, PVDF, and Viton could be entirely banned, with the exception of API molecules themselves. The implications of such a ban for the chemical and (bio)pharma industries in Europe cannot be overstated. The EU Proposal is currently out for public consultation, and the purpose of this Perspective is both to raise awareness and to encourage contributions to the consultation process. Comments to the EU must be received by the deadline of 23:59 (Helsinki time) on September 25, 2023.

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一项在整个欧盟范围内禁止生产、供应和使用所有含氟聚合物和大多数含氟试剂的提案

提议修改欧盟法律，禁止生产、供应和使用大多数全氟和多氟烷基物质(PFAS)材料。欧盟提议的PFAS定义非常广泛，包括大多数氟烷基材料，无论分子量如何。因此，除了原料药分子本身外，从简单的三氟乙酸到含氟中间体再到聚四氟乙烯、PVDF和Viton等聚合物的试剂都可能被完全禁止。这一禁令对欧洲化学和(生物)制药行业的影响怎么强调也不为过。欧盟提案目前正在进行公众咨询，本展望的目的是提高认识并鼓励对咨询过程作出贡献。提交给欧盟的意见必须在2023年9月25日23:59(赫尔辛基时间)截止日期前收到。

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来源期刊

Organic Process Research & Development 化学-应用化学

CiteScore

6.90

自引率

14.70%

发文量

251

审稿时长

2 months

期刊介绍： The journal Organic Process Research & Development serves as a communication tool between industrial chemists and chemists working in universities and research institutes. As such, it reports original work from the broad field of industrial process chemistry but also presents academic results that are relevant, or potentially relevant, to industrial applications. Process chemistry is the science that enables the safe, environmentally benign and ultimately economical manufacturing of organic compounds that are required in larger amounts to help address the needs of society. Consequently, the Journal encompasses every aspect of organic chemistry, including all aspects of catalysis, synthetic methodology development and synthetic strategy exploration, but also includes aspects from analytical and solid-state chemistry and chemical engineering, such as work-up tools，process safety, or flow-chemistry. The goal of development and optimization of chemical reactions and processes is their transfer to a larger scale; original work describing such studies and the actual implementation on scale is highly relevant to the journal. However, studies on new developments from either industry, research institutes or academia that have not yet been demonstrated on scale, but where an industrial utility can be expected and where the study has addressed important prerequisites for a scale-up and has given confidence into the reliability and practicality of the chemistry, also serve the mission of OPR&D as a communication tool between the different contributors to the field.

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