The role of tranexamic acid in the treatment of giant hemangiomas in newborns.

A B Morad, K L McClain, A K Ogden
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Abstract

Giant hemangiomas occurring in the neonatal period often present a therapeutic challenge, especially when confounded by consumptive coagulopathy (Kasabach-Merritt syndrome). We treated three infants with tranexamic acid after therapy with corticosteroids was ineffective. One patient had a partial response. The remaining two developed progressive disease.

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氨甲环酸在新生儿巨血管瘤治疗中的作用。
发生在新生儿期的巨大血管瘤通常是一个治疗挑战,特别是当合并消耗性凝血功能障碍(卡萨巴赫-梅里特综合征)时。我们用氨甲环酸治疗三名婴儿在用皮质类固醇治疗无效后。一名患者有部分反应。其余2例发展为进行性疾病。
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