Methadone maintenance and the likelihood of risky needle-sharing.

J R Caplehorn, M W Ross
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引用次数: 112

Abstract

Survey data were used to study the association of methadone maintenance and needle-sharing. An ordinal scale of HIV risk was derived from the number of persons from whom subjects reported accepting a used needle and syringe in the 6 months prior to interview. The odds of respondents in methadone maintenance being in the higher risk group were half those of daily heroin users not in treatment for all three transitions in a four-level ordinal scale of risk (OR 0.55, 95% CL 0.33 to 0.90, ordinal logistic regression). This association disappeared when methadone patients who had not injected in the month prior to interview were excluded from the analysis. Subjects' knowledge concerning HIV and AIDS had no measurable association with the outcome. It is concluded that methadone maintenance reduces heroin addicts' risk of infection with HIV by reducing the likelihood of their injecting drugs rather than by changing their injecting behavior.

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美沙酮维持与共用针头风险的可能性。
利用调查数据研究美沙酮维持与共用针头的关系。根据受访者在访谈前6个月内接受过用过的针头和注射器的人数,得出HIV风险的序数。在四个水平的有序风险量表中,美沙酮维持的应答者处于高风险组的几率是每日海洛因使用者未接受所有三个过渡治疗的一半(OR 0.55, 95% CL 0.33至0.90,有序逻辑回归)。当访谈前一个月未注射美沙酮的患者被排除在分析之外时,这种关联消失了。受试者关于HIV和艾滋病的知识与结果没有可测量的关联。结论是美沙酮维持治疗降低海洛因依赖者感染HIV的风险是通过降低他们注射毒品的可能性,而不是通过改变他们的注射行为。
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