[The effect of low and high molecular weight dextrans on selected lipid parameters in serum. Part 3].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete Pub Date : 1993-08-01

C Rühlmann, M Koksch, K Hohdorf, B Kuklinski

引用次数: 0

Abstract

After a ten-day treatment of 21 patients with low molecular weight dextran (MW = 40,000), a decrease in the plasma concentrations of total cholesterol of 25%, LDL-cholesterol of 32% and apoprotein B of 22% was observed. The HDL fraction only showed a reduction of 10%. These dextran effects were dose-dependent. During the post-treatment period of 20 days a continuous increase in the lipid parameters to the preinfusion values was demonstrated. Dextran caused stronger lipid changes in HLP patients than in normolipaemics.

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低分子量和高分子量右旋糖酐对血清选定脂质参数的影响。第3部分)。

21例患者接受低分子量葡聚糖(MW = 40000)治疗10天后，血浆总胆固醇浓度下降25%，低密度脂蛋白胆固醇下降32%，载脂蛋白B下降22%。高密度脂蛋白含量只下降了10%。这些葡聚糖效应是剂量依赖性的。在治疗后20天，脂质参数持续增加到注射前的值。右旋糖酐在HLP患者中引起的脂质变化强于正常血脂患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete

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