An economic evaluation of four work site based cardiovascular risk factor interventions.

B Oldenburg, N Owen, M Parle, M Gomel
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引用次数: 29

Abstract

We used outcome data from a randomized work site intervention trial to examine the cost-effectiveness of four cardiovascular disease (CVD) risk reduction programs: health risk assessment (HRA), risk factor education (RFE), behavioral counseling (BC), and behavioral counseling plus incentives (BCI). Composite CVD risk scores were derived from measures of serum total cholesterol, blood pressure, number of cigarettes smoked, body mass index, and aerobic capacity. The economic evaluation of the programs focused on the subset of costs most sensitive to the differences between the interventions, and a sensitivity analysis examined some of the relevant cost variations. At the 6-month follow-up (i.e., the "action" or initiation stage of lifestyle change), the RFE, BC, and BCI interventions produced a significant reduction in cardiovascular risk. Incremental analyses demonstrated RFE to be more cost-effective, but not as clinically effective as BC; BC was more cost-effective than RFE when assessment costs were included, and BCI was judged to be the least cost-effective. At the 12-month follow-up (i.e., the "maintenance" stage of lifestyle of change), BC was the only program found to produce a significant reduction in CVD risk. Individualized behavioral counseling was found to be a cost-effective strategy for the initiation and maintenance of CVD risk factor reduction.

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四种工作场所心血管危险因素干预的经济评价。
我们使用随机工作场所干预试验的结果数据来检验四种心血管疾病(CVD)风险降低方案的成本效益:健康风险评估(HRA)、风险因素教育(RFE)、行为咨询(BC)和行为咨询加激励(BCI)。综合心血管疾病风险评分来源于血清总胆固醇、血压、吸烟数量、体重指数和有氧能力。项目的经济评估集中在对干预措施之间的差异最敏感的成本子集上,敏感性分析检查了一些相关的成本变化。在6个月的随访中(即生活方式改变的“行动”或开始阶段),RFE、BC和BCI干预显著降低了心血管风险。增量分析表明,RFE更具成本效益,但临床效果不如BC;当包括评估费用时,BC比RFE更具成本效益,而BCI被认为是最不具成本效益的。在12个月的随访中(即生活方式改变的“维持”阶段),BC是唯一发现能显著降低心血管疾病风险的项目。个体化行为咨询被认为是降低心血管疾病危险因素开始和维持的一种经济有效的策略。
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