Recombinant vaccine development: a novel approach to ectoparasite control. A review of development of a recombinant vaccine for hypodermosis based on hypodermin A.

K B Temeyer, J H Pruett, I Kuhn, J Files
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Abstract

Cattle grubs (Hypoderma lineatum and H. bovis) are obligate parasites of cattle for most of their one year life cycle. Previously exposed animals become resistant to productive reinfestation, presumably as a result of immune system involvement, suggesting potential control by vaccination. Research progress towards development and utilization of a recombinant subunit vaccine for hypodermosis is described.

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重组疫苗研制:控制体外寄生虫的新方法。基于浅皮素A的重组皮下病疫苗的研究进展。
牛蛴螬(线状下皮病和牛h.b vis)在其一年生命周期的大部分时间里都是牛的专性寄生虫。先前接触过的动物可能由于免疫系统的参与而对再植产生抗性,这表明可能通过接种疫苗进行控制。本文介绍了一种重组亚单位疫苗的研制和利用的研究进展。
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