Peripheral Blood Progenitor Cell Transplantation for Hematological Malignancies

Reiffers J.
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Abstract

It has been demonstrated that it is possible to mobilize hematopoietic progenitor cells from the bone marrow into the peripheral blood, from which they can be collected by apheresis and used for transplantation. Although the clinical results obtained using this approach have not been compared in a randomized trial to those obtained using bone marrow, it appears that this method has certain advantages. These, together with future developments, are discussed in this review.

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外周血祖细胞移植治疗血液恶性肿瘤
已经证明,将造血祖细胞从骨髓中动员到外周血中是可能的,这些细胞可以通过分离收集并用于移植。虽然使用该方法获得的临床结果尚未在随机试验中与使用骨髓获得的临床结果进行比较,但似乎该方法具有一定的优势。本文将讨论这些以及未来的发展。
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Editorial Expression of Cell Surface Markers during Differentiation of CD34+, CD38−/lo Fetal and Adult Bone Marrow Cells Isolation of CD34-Positive Hematopoietic Progenitor Cells Ex Vivo Hematopoietic Progenitor Cell Expansion T-Cell Depletion and Manipulation in Allogeneic Hematopoietic Cell Transplantation
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