{"title":"Detection of Minimal Residual Disease in Autologous Grafts","authors":"Moss Thomas J.","doi":"10.1006/immu.1994.1060","DOIUrl":null,"url":null,"abstract":"<div><p>There is increasing evidence that the presence of tumor cells within autologous hematopoietic cell grafts may increase the risk of relapse of disease post-transplant. The sensitive detection of minimal residual disease is therefore central to improving the outcome of autologous transplantation, irrespective of the source of the graft. This review presents a comparative evaluation of the sensitivity and specificity of the currently available methods for tumor detection.</p></div>","PeriodicalId":79341,"journal":{"name":"ImmunoMethods","volume":"5 3","pages":"Pages 226-231"},"PeriodicalIF":0.0000,"publicationDate":"1994-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/immu.1994.1060","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ImmunoMethods","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1058668784710606","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
There is increasing evidence that the presence of tumor cells within autologous hematopoietic cell grafts may increase the risk of relapse of disease post-transplant. The sensitive detection of minimal residual disease is therefore central to improving the outcome of autologous transplantation, irrespective of the source of the graft. This review presents a comparative evaluation of the sensitivity and specificity of the currently available methods for tumor detection.
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