Different tracers and stressors in patients with coronary artery disease: how to standardize clinical questions and nuclear cardiology answers.

P Marzullo, G Sambuceti, A Gimelli, A Giorgetti, O Parodi
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Abstract

The recent introduction of new tracers and stressors has increased the number of combinations of techniques that can be used for the diagnostic and prognostic stratification of patients with coronary artery disease. However, these new techniques still need to be standardized for clinical use. Thallium-201 scintigraphy is at present the most common method to assess transient ischemia and viability in patients. Dynamic exercise and dipyridamole show similar incidence of major cardiac complications and their use can be considered sufficiently safe. Further experimental and multicenter clinical studies are needed for 99mTc-Sestamibi and 99mTc-Teboroxime and for new stressors such as adenosine and dobutamine.

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冠状动脉疾病患者的不同示踪剂和应激源:如何规范临床问题和核心脏病学答案。
最近引入的新示踪剂和应激源增加了可用于冠状动脉疾病患者诊断和预后分层的技术组合的数量。然而,这些新技术仍需要标准化以供临床使用。铊-201显像是目前评估患者短暂性缺血和生存能力最常用的方法。动态运动和双嘧达莫显示出相似的主要心脏并发症发生率,它们的使用可以被认为是足够安全的。99mTc-Sestamibi和99mtc - teboroxme以及新的应激源(如腺苷和多巴酚丁胺)需要进一步的实验和多中心临床研究。
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