Lourenco Bozzo PhD , Oslei paes de Almeida PhD , Crispian Scully PhD, MD, MDS (FDSRCPS, FFDRCSI, FDSRCS, FRCPath) , Michael J. Aldred BDS, PhD (FDS, MRCPath)
{"title":"Hereditary gingival fibromatosis","authors":"Lourenco Bozzo PhD , Oslei paes de Almeida PhD , Crispian Scully PhD, MD, MDS (FDSRCPS, FFDRCSI, FDSRCS, FRCPath) , Michael J. Aldred BDS, PhD (FDS, MRCPath)","doi":"10.1016/0030-4220(94)90037-X","DOIUrl":null,"url":null,"abstract":"<div><p>A Brazilian family with hereditary gingival fibromatosis is described with multiple affected subjects in four generations. A total of 50 (48%), of 105 at-risk offspring in a family of 132 members were affected, consistent with an autosomal dominant mode of inheritance. This family appears to represent the largest pedigree with this condition reported in the literature.</p></div>","PeriodicalId":100992,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology","volume":"78 4","pages":"Pages 452-454"},"PeriodicalIF":0.0000,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0030-4220(94)90037-X","citationCount":"102","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Surgery, Oral Medicine, Oral Pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/003042209490037X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 102
Abstract
A Brazilian family with hereditary gingival fibromatosis is described with multiple affected subjects in four generations. A total of 50 (48%), of 105 at-risk offspring in a family of 132 members were affected, consistent with an autosomal dominant mode of inheritance. This family appears to represent the largest pedigree with this condition reported in the literature.