[Patients with high spinal cord injuries: evaluation of diaphragmatic function, indication of electrophrenic ventilation].

J F Brule, B Leriche, J Normand, P Morel
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Abstract

Electrophrenic Respiration (REP) is a technic specially reserved to the patients with a first motoneuron disease but having moreover normal phrenic nerve, diaphragm and lungs. Electrical pulse trains are applied to the phrenic nerve by a surgically implanted electrode. They produce rhythmic inspiratory diaphragm contractions; expiratory time is passive. The energy is delivered by a transcutaneous radiofrequency external pacer. Before to decide to implant a REP device, it should be wait for a sufficient time to avoid either a possible return to a spontaneous breathing or, on the contrary, a peripheral nerve disease initially unrecognized. After regularly repeated external detection exams, surgery must be done gently on a stabilised patient, out of infection and, if possible, without intellectual trouble. The training needs a long time (many months) since to become fatigue-resistant a paced muscle must be trained progressively and durably. In that way the results are generally good, as the 13 patients we have implanted may give an evidence.

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【高位脊髓损伤患者:膈肌功能的评估,颅电通气的指征】。
膈电呼吸术(REP)是一种专门用于原发性运动神经元疾病而膈神经、膈肌和肺又正常的患者的技术。通过手术植入的电极将电脉冲序列施加到膈神经上。它们产生有节奏的吸气隔膜收缩;呼气时间是被动的。能量由经皮射频外部起搏器传递。在决定植入REP装置之前,应等待足够的时间,以避免可能恢复自主呼吸或相反,最初未被识别的周围神经疾病。在定期重复的外部检测检查之后,手术必须在稳定的病人身上轻轻地进行,没有感染,如果可能的话,没有智力障碍。这种训练需要很长时间(好几个月),因为要使有节奏的肌肉具有抗疲劳能力,就必须逐步地、持久地训练。这样做的结果通常是好的,因为我们植入的13个病人可能会提供证据。
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