Declining incidence of amputation for arterial disease in Scotland

J.P. Pell , F.G.R. Fowkes , C.V. Ruckley , J. Clarke , S. Kendrick , J.H. Boyd
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引用次数: 37

Abstract

Objectives:

To determine time trends and geographical variations in the incidence of major amputation for peripheral arterial disease and whether lower rates of amputation were related to higher rates of arterial reconstruction.

Design:

Analysis of Scottish hospital discharge data.

Setting:

Scotland 1981–1990.

Materials:

Patients undergoing major amputation or arterial reconstruction for peripheral arterial disease.

Chief outcome measures:

Time trends in age-sex standardised rates of major amputation and arterial reconstruction, and correlation between the rates of these operations by health board.

Main results:

In Scotland, between 1981 and 1990, the incidence of major amputation fell by 22% (p < 0.001). Inconsistencies were observed within different age-sex groups. In the population under 65 years of age the incidence of amputation fell by 45% (p < 0.001), whereas in those over 65 years the incidence increased by 54% (p < 0.001). Amputation rates fell in men but a paradoxical increase was observed in women. Between 1981 and 1990, rates of arterial reconstruction doubled (p < 0.001), with an increase in all age-sex groups. Rates of amputation and reconstruction varied between health boards of residence, with a positive correlation (r = 0.5) between rates of operations within health board. Therefore areas with higher reconstruction rates tended to have higher amputation rates.

Conclusions:

In Scotland, the incidence of amputation has fallen during a period when reconstruction rates have risen greatly. However inconsistencies in time trends by age-sex groups, and the lack of an inverse correlation by health board of residence, suggest that fewer amputations are unlikely to be due solely to an increase in reconstructive surgery.

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苏格兰因动脉疾病而截肢的发病率下降
目的:确定外周动脉疾病主要截肢发生率的时间趋势和地理变化,以及较低的截肢率是否与较高的动脉重建率相关。设计:对苏格兰医院出院数据进行分析。苏格兰设置:1981 - 1990。材料:因外周动脉病变而行大截肢或动脉重建的患者。主要结果衡量指标:卫生委员会统计的年龄-性别标准化大截肢和动脉重建率的时间趋势,以及这些手术率之间的相关性。主要结果:在苏格兰,1981年至1990年间,主要截肢的发生率下降了22% (p <0.001)。在不同年龄-性别组中观察到不一致性。在65岁以下人群中,截肢的发生率下降了45% (p <0.001),而在65岁以上的人群中发病率增加了54% (p <0.001)。截肢率在男性中下降,但在女性中却出现了矛盾的上升。1981年至1990年间,动脉重建率翻了一番(p <0.001),在所有年龄-性别群体中均有所增加。各居住地卫生局的截肢率和重建率各不相同,卫生局内的手术率呈正相关关系(r = 0.5)。因此,重建率高的区域往往有较高的截肢率。结论:在苏格兰,截肢发生率下降,而重建率却大幅上升。然而,不同年龄性别群体在时间趋势上的不一致,以及居住卫生委员会缺乏负相关性,表明截肢减少不太可能仅仅是由于重建手术的增加。
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