Oral hairy leukoplakia in nonimmunosuppressed patients

Francina Lozada-Nur DDS, MS , John Robinson DDS , Joseph A. Regezi DDS, MS
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引用次数: 44

Abstract

Hairy leukoplakia was first described in association with HIV infection. Today hairy leukoplakia has come to represent a sign of immunosuppression and not just of HIV infection. Although molecular mechanisms have not been fully elucidated, Epstein-Barr virus appears to play a significant role in its etiopathogenesis. We present four cases that illustrate that HL may be seen in non-HIV and nonimmunocompromised patients. The use of high potency topical steroids for the treatment of oral vesiculoerosive diseases seems to have been a contributing factor in two of these cases.

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非免疫抑制患者的口腔毛状白斑
毛状白斑最初被描述为与HIV感染有关。如今,毛状白斑已经成为免疫抑制的标志,而不仅仅是HIV感染的标志。尽管分子机制尚未完全阐明,但Epstein-Barr病毒似乎在其发病机制中起重要作用。我们提出了四个病例,说明HL可能出现在非hiv和非免疫功能低下的患者。在其中两个病例中,使用高效外用类固醇治疗口腔囊泡糜烂性疾病似乎是一个促成因素。
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