The effect of actinomycin D on the megakaryocytic line in rat.

J Janoutová, Z Likovský
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Abstract

Four-day administration of actinomycin D to the albino rat in daily doses of 25 micrograms/kg decreased--in relation to all blood cells of the bone marrow--the values of the more mature stages of the megakaryocytic line, i.e. megakaryocytes and naked megakaryocyte nuclei. The number of megakaryoblasts was not influenced.

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放线菌素D对大鼠巨核细胞系的影响。
对白化大鼠给予放线菌素D四天,每日剂量为25微克/公斤,相对于骨髓的所有血细胞,巨核细胞系更成熟阶段的价值,即巨核细胞和裸巨核细胞核的价值降低。巨核细胞的数量不受影响。
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