Genetic toxicology of vinyl chloride—a review

A.K. Giri
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引用次数: 36

Abstract

Vinyl chloride (VC) is a colorless gas with a mild, sweet odor. It is extensively used in the production of vinyl chloride polymer, copolymer resin, packaging materials, wire and cable coatings as well as in industrial and laboratory intermediates. It is toxic and also carcinogenic in experimental animals. The wide human exposure to this compound in different industries throughout the world causes great concern for human health. In the present review an attempt has been made to evaluate and update the genotoxic effects of vinyl chloride based on the available literature.

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氯乙烯的遗传毒理学研究进展
氯乙烯(VC)是一种无色气体,具有温和的甜味。广泛用于生产氯乙烯聚合物、共聚物树脂、包装材料、电线电缆涂料以及工业和实验室中间体。在实验动物中,它是有毒的,也是致癌的。人类在世界各地的不同行业中广泛接触这种化合物,这引起了人们对人类健康的极大关注。在本综述中,本文试图在现有文献的基础上对氯乙烯的遗传毒性效应进行评价和更新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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DNA adducts and chronic degenerative diseases. Pathogenetic relevance and implications in preventive medicine Carbon tetrachloride: Genetic effects and other modes of action Dr. Hans F. Stich, Professor Emeritus of the University of British Columbia, 1927–1995 Product review Foreword
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