Tendon jerks in Parkinson's disease.

J P Hammerstad, K Elliott, E Mak, M Schulzer, S Calne, D B Calne
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引用次数: 9

Abstract

Tendon reflexes were examined in 119 patients with idiopathic parkinsonism (IP) and 40 spouse controls to estimate the type and frequency of any alterations in the reflexes. Forty one of 119 patients and 2 of 40 controls had reflex ratings of 3+ at two or more sites (p < 0.001). There was no correlation of reflex score with the severity of disease or with the cardinal signs of IP. In 21 patients with asymmetric tendon jerks the side with the more active reflexes correlated with the side with greater parkinsonian signs. We conclude that an increase in tendon jerks is a feature of IP. The pathophysiology of this change in reflexes should be investigated further to establish if it is a heretofore overlooked manifestation of basal ganglia dysfunction or a link with other neurodegenerative diseases.

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帕金森氏症的肌腱痉挛。
对119例特发性帕金森病患者(IP)和40例配偶对照进行肌腱反射检查,以估计反射变化的类型和频率。119名患者中的41名和40名对照中的2名在两个或更多部位的反射评分为3+ (p < 0.001)。反射评分与疾病的严重程度或IP的主要体征没有相关性。在21例不对称肌腱痉挛患者中,反射更活跃的一侧与帕金森症状更严重的一侧相关。我们得出结论,肌腱痉挛的增加是IP的一个特征。这种反射变化的病理生理学应该进一步研究,以确定它是迄今为止被忽视的基底神经节功能障碍的表现,还是与其他神经退行性疾病有关。
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