[Benzodiazepines in blood samples of alcohol intoxicated drivers].

Blutalkohol Pub Date : 1994-05-01
L Ulrich
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Abstract

1,000 blood samples from drivers tested for alcohol were screened specifically for active constituents and metabolites of medicines of the benzodiazepine class. 42 blood samples contained benzodiazepines and a total of eight different active constituents were detected. The active constituents of Valium, Vegesan or Tranxilium, Lexotanil and Seresta have to be dealt with primarily. In addition to benzodiazepine 35 samples showed an alcohol level of over 0.08%. This raised the question of whether the benzodiazepine level measured in the blood samples would intensify the effect of the alcohol. Four categories were formed in order to be able to compare the levels of the various benzodiazepines. According to this categorisation the benzodiazepine concentration was classed as very high in 4 cases, high in 7 cases, moderate in 26 cases and low in 10 cases.

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[醉酒司机血液样本中的苯二氮卓类药物]。
从司机身上采集的1000份血液样本进行了酒精测试,专门筛选苯二氮卓类药物的活性成分和代谢物。42份血液样本中含有苯二氮卓类药物,共检测到8种不同的活性成分。安定、Vegesan或Tranxilium、Lexotanil和Seresta的有效成分必须首先处理。除了苯二氮卓类药物,35份样本显示酒精含量超过0.08%。这就提出了一个问题,即血液样本中测量的苯二氮卓类药物水平是否会加强酒精的作用。为了能够比较各种苯二氮卓类药物的含量,形成了四个类别。根据这一分类,苯二氮卓类药物浓度分为非常高4例、高7例、中等26例和低10例。
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