{"title":"Long-term survivors of HIV infection.","authors":"J A Levy","doi":"10.1080/21548331.1994.11443088","DOIUrl":null,"url":null,"abstract":"<p><p>The persistent immune competence seen in a small percentage of HIV-infected individuals reflects the heterogeneity of both the virus and the host. Some HIV strains, for example, are more cytopathic than others. Host factors that promote longer survival lack \"enhancing\" antibodies, an appropriate balance of two crucial CD4+ cell subsets and their cytokines, and a strong CD8+ cell antiviral response.</p>","PeriodicalId":77164,"journal":{"name":"Hospital practice (Office ed.)","volume":"29 10","pages":"41-4, 47, 51-2"},"PeriodicalIF":0.0000,"publicationDate":"1994-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.1994.11443088","citationCount":"37","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hospital practice (Office ed.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/21548331.1994.11443088","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 37
Abstract
The persistent immune competence seen in a small percentage of HIV-infected individuals reflects the heterogeneity of both the virus and the host. Some HIV strains, for example, are more cytopathic than others. Host factors that promote longer survival lack "enhancing" antibodies, an appropriate balance of two crucial CD4+ cell subsets and their cytokines, and a strong CD8+ cell antiviral response.
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