{"title":"Human monoclonal antibodies: recent achievements.","authors":"D R Burton, C F Barbas","doi":"10.1080/21548331.1994.11443111","DOIUrl":null,"url":null,"abstract":"<p><p>The latest developments include an anti-HIV antibody that has 1,000 times the affinity of natural antibody and that neutralizes primary clinical isolates, and an anti-RSV antibody that reduces viral titers in mice by 12,000-fold within 24 hours.</p>","PeriodicalId":77164,"journal":{"name":"Hospital practice (Office ed.)","volume":"29 11","pages":"111, 114-6, 119 passim"},"PeriodicalIF":0.0000,"publicationDate":"1994-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.1994.11443111","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hospital practice (Office ed.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/21548331.1994.11443111","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
The latest developments include an anti-HIV antibody that has 1,000 times the affinity of natural antibody and that neutralizes primary clinical isolates, and an anti-RSV antibody that reduces viral titers in mice by 12,000-fold within 24 hours.