Effects of flumazenil (Ro15-1788) on blood glucose and serum lipids in normoglycemic and normolipidemic rats.

J Horák, B Cuparencu
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Abstract

The intraperitoneal administration of flumazenil, an imidazoldiazepine with selective antagonistic properties on the central benzodiazepine receptors, induced in normoglycemic-normolipidemic rats a significant increase in blood glucose levels and significant decreases in the serum lipids.

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氟马西尼(Ro15-1788)对正常血糖和正常血脂大鼠血糖和血脂的影响。
氟马西尼是一种对中枢苯二氮卓受体具有选择性拮抗特性的咪唑二氮卓类药物,腹腔注射氟马西尼可诱导正常血糖-正常血脂大鼠血糖水平显著升高,血清脂质显著降低。
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