[Hemodynamic study of acute neurogenic pulmonary edema in children].

Pediatrie Pub Date : 1993-01-01
C Jourdan, J Convert, C Rousselle, J Wasylkiewicz, V Mircevski, C Mottolese, C Lapras
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Abstract

Acute neurogenic pulmonary edema (NPE) can dramatically complicate a serious brain injury. From bibliographic data and four personal cases documented by and haemodynamical study, the authors analyse the pathophysiological mechanisms and the haemodynamical changes resulting from massive sympathic outflow, the main mechanism of NPE being haemodynamical rather than lesional. This rare complication needs to be recognized in order to undergo an intensive care treatment generally leading to a favourable evolution. This treatment lies on circulatory and ventilatory supports with positive and expiratory pressure in order to maintain an optimal oxygenation and an optimal cerebral perfusion pressure. With this treatment the outcome of NPE is usually favourable with complete recovery within 2 to 5 days.

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儿童急性神经源性肺水肿的血流动力学研究。
急性神经源性肺水肿(NPE)可使严重脑损伤严重复杂化。本文结合文献资料和4例血流动力学研究,分析了大量交感神经流出的病理生理机制和血流动力学变化,认为NPE的主要机制是血流动力学而非病变性。这种罕见的并发症需要确认,以便进行重症监护治疗,通常会导致有利的进展。这种治疗依靠循环和通气支持,以维持最佳氧合和最佳脑灌注压。通过这种治疗,NPE的结果通常是有利的,在2至5天内完全恢复。
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