Uveitis in nephrotic syndrome.

Abstract

A 35-year-old Japanese woman with nephrotic syndrome due to mesangial proliferative glomerulonephritis was treated with steroid hormone for 5 years and suddenly developed uveitis in the left eye. She had many cells in the anterior chamber, fine granular keratitic precipitates on the posterior surface of the cornea and retinal edema around the optic disc. Diabetes mellitus had been diagnosed, but it was considered to be steroid diabetes mellitus. This patient showed depressed spontaneous blastogenesis. Since nephrotic syndrome is occasionally associated with an immune-mediated process, uveitis in this case might be related to an immunity disorder.