Hormonal and immunologic methods in the diagnosis and treatment of patients with benign ovarian tumors and endometriotic cysts.

International Journal of Fertility Pub Date : 1993-03-01
L V Adamyan, N D Fanchenko, M L Alexeyeva, Andreyeva YeN, Novikov YeA, I Jahan
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Abstract

Objective: To compare efficacy of various methods for characterizing endometriosis and benign ovarian tumors.

Design: Two parallel groups of patients, 54 with endometriotic ovarian cysts and 48 with benign tumors.

Setting: Central clinic.

Patients: Patients referred from all regions over a 5-year period.

Outcome measures: Estrogen Estrogen and progesterone receptor levels of endometrium and endometriotic foci, CA-125 concentration, and estradiol, progesterone, LH, and testosterone blood levels.

Results: LH levels elevated during follicular phase in patients; estradiol levels reduced; receptor levels abnormal in endometriosis, but not in benign ovarian cysts.

Conclusions: Hormone therapy is adequate treatment for endometriotic cysts. CA-125 is not a reliable indicator for differential diagnosis.

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良性卵巢肿瘤与子宫内膜异位囊肿的激素与免疫学诊断与治疗。
目的:比较子宫内膜异位症与良性卵巢肿瘤不同诊断方法的疗效。设计:两组平行患者,54例子宫内膜异位性卵巢囊肿和48例良性肿瘤。地点:中心诊所。患者:5年内来自各地区的患者。结果测量:雌激素子宫内膜和子宫内膜异位灶的雌激素和孕激素受体水平,CA-125浓度,以及雌二醇、孕酮、黄体生成素和睾酮血液水平。结果:患者卵泡期LH水平升高;雌二醇水平降低;受体水平异常在子宫内膜异位症,但在良性卵巢囊肿。结论:激素治疗是治疗子宫内膜异位囊肿的有效方法。CA-125不是鉴别诊断的可靠指标。
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