Serum alpha 1-antichymotrypsin is not a useful marker for Alzheimer's disease or dementia in Parkinson's disease.

M A Kuiper, G J van Kamp, P L Bergmans, P Scheltens, E C Wolters
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引用次数: 13

Abstract

We measured serum alpha 1-antichymotrypsin (ACT) levels in patients with Alzheimer's disease (AD), Parkinson's disease (PD), Multiple System Atrophy (MSA) and age-matched controls to evaluate whether serum ACT levels in AD patients were elevated and whether ACT levels in PD patients with dementia differed from those in PD or AD. None of the patient groups displayed an increase in ACT levels. We conclude that serum ACT is not useful as a marker, nor in AD nor in dementia in PD.

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血清α 1-抗凝乳胰蛋白酶不是阿尔茨海默病或帕金森病痴呆的有用标志物。
我们测量了阿尔茨海默病(AD)、帕金森病(PD)、多系统萎缩(MSA)患者和年龄匹配对照者的血清α 1-抗凝乳胰蛋白酶(ACT)水平,以评估AD患者的血清ACT水平是否升高,以及PD合并痴呆患者的ACT水平是否与PD或AD患者不同。所有患者组均未显示ACT水平升高。我们的结论是,血清ACT不能作为一种标志物,在AD和PD痴呆中也不能。
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