Functional carriers for bone morphogenetic proteins.

T S Lindholm, T J Gao
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Abstract

This review covers advances in current researches on delivery systems for bone morphogenetic protein. In summary, it notes that the diversity of carriers, inorganic, organic and synthetic composite, have possessed physiochemical and biological properties and efficacy of delivery of bone morphogenetic protein promoting bone induction in experimental animals. It also traces a new trend in research on carrier systems for bone morphogenetic protein. A desirable carrier of BMP will bridge basic research with clinical application of bone morphogenetic protein.

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骨形态发生蛋白的功能载体。
本文综述了近年来骨形态发生蛋白递送系统的研究进展。综上所述,无机载体、有机载体和合成复合载体的多样性,在实验动物中均具有输送骨形态发生蛋白促进骨诱导的理化生物学特性和功效。这也为骨形态发生蛋白载体系统的研究开辟了新的方向。理想的BMP载体将为骨形态发生蛋白的基础研究和临床应用架起桥梁。
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