{"title":"Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes.","authors":"S Bauguil-Caspar, J Arnaud, J Kuhlmann, C Geisler, B Rubin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains.</p>","PeriodicalId":79340,"journal":{"name":"Immunodeficiency","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunodeficiency","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains.
tcr - α, β和tcr - γ, δ /CD3复合物的生物合成。
用WT31单抗(Tcr- α, β)或Tcr- δ 1单抗(Tcr- γ, δ)检测转染J76- α cDNA或J76 Tcr- α突变cDNA (J79)的Jurkat J76克隆、LYON L12.37克隆和L12.37细胞Tcr/CD3复合物的膜表达。转染J76 tcr - α cDNA的LYON细胞具有胞内tcr - γ、δ链,转染J79 tcr - α cDNA的LYON细胞具有胞内tcr - α (M)、β链。
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