Acute myocardial infarction complicating prothrombin complex concentrate therapy in an 8-year-old boy with hemophilia A and factor VIII inhibitor.

G Karayalcin, B Goldberg, I Cherrick, C Kurer, F Bierman, P Lanzkowsky
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Abstract

Purpose: An 8-year-old boy with mild hemophilia A and inhibitors developed an acute myocardial infarction during treatment with prothrombin complex concentrates.

Conclusions: This rare complication warrants restriction of dosage and length of treatment with these products to the recommended guidelines. It also appears that noninvasive cardiac monitoring of these patients is beneficial.

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急性心肌梗死合并凝血酶原复合物浓缩治疗1例8岁男孩血友病A和因子VIII抑制剂
目的:一名患有轻度血友病A和抑制剂的8岁男孩在接受凝血酶原复合物浓缩物治疗期间发生急性心肌梗死。结论:这种罕见的并发症需要根据推荐指南限制这些产品的剂量和治疗时间。对这些患者进行无创心脏监测似乎也是有益的。
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